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SR One is the corporate venture capital arm of GlaxoSmithKline. The firm invests globally in emerging life science companies that are pursuing innovative science which will significantly impact medical care. We have a team of investment professionals, located in the US and UK. As a Team, our experience spans basic science, industry and the market. We take an active role in our portfolio companies and work with management teams and our fellow venture investors to create significant value. Our current portfolio includes approximately 35 private and public companies and since our founding in 1985, we have invested over $830MM in the biotech space. Our expanded remit also focuses on maximizing the value of GSK technological innovation to establish new businesses and revenue opportunities across a range of industries.

Regenevita is a WORLD LEADER in use of your own cells, coupled with important natural chemicals stored within our platelets, to be safely and effectively used to improve and enhance our body’s ability to repair damaged or aging tissues. With more than 20 years experience with Biocellular Regenerative Treatments in medical-surgical practice, we offer treatments which can greatly improve your ability to maintain and restore normal activities or appearance. Just the term “biocellular” says it all. We use your own platelets and cells from within your own fat tissue to enhance your ability to enjoy pain-free function and activities.

In 2014 we continued to build on our legacy of above market performance by strengthening our leadership in Orthopaedics, Medical and Surgical (MedSurg) and Neurotechnology & Spine. We delivered solid growth and financial results, completed a number of acquisitions, opened a new European Regional Headquarters (RHQ) and articulated our unique culture through a new mission statement and core values.

Formally known as The State University of New York Health Science Center at Brooklyn—but better known to our patients and Brooklyn neighbors as SUNY Downstate Medical Center—we are older than the Brooklyn Bridge. We trace our roots back to 1860, when a school of medicine was founded at the Long Island College Hospital. The new college’s faculty revolutionized medical education in this country by bringing the teaching of medicine to the hospital bedside, thus rejecting the idea that physicians should be trained exclusively in university lecture halls.

Nobel Prize Winner in Medicine
Dr. Robert Furchgott

Today, SUNY Downstate is one of the nation’s leading urban medical centers. SUNY Downstate comprises a College of Medicine, College of Health Related Professions, College of Nursing, School of Graduate Studies, School of Public Health, and University Hospital of Brooklyn.

The quality of our education, research, and patient care programs was confirmed with the awarding of theNobel Prize in Medicine to Dr. Robert Furchgott, a member of our School of Graduate Studies faculty since 1956. Dr. Furchgott’s identification of nitric oxide as a signalling molecule important in vascular health has revolutionized care for heart, stroke, impotence, and other diseases.

As the only academic medical center in Brooklyn, we serve a large population–over 2.3 million people–and one that is among the most diverse in the world. We are also an engine of opportunity for students interested in pursuing careers in health care. Many of our students are the first in their families to attend college.

More physicians who practice medicine in New York City received their training at our College of Medicine than any other medical center in the country. Nationally, our medical school ranks seventh in the number of graduates who are now engaged in academic medicine. Here in Brooklyn, our impact is even greater. We have trained nearly half of all doctors practicing in a number of specialty areas.

Our College of Health Related Professions and College of Nursing also play a unique role in the borough and the city. We have the oldest midwifery program in the country, and we recently made history again by establishing a joint program between the two colleges that trains midwives who are not nurses. The College of Nursing is particularly proud of its role in educating minority students. Approximately three-fourths of the students are minority-group members, and many are recent immigrants.

University Hospital of Brooklyn is the borough’s only hospital located at an academic medical center. As such, it offers the most advanced and comprehensive care in Brooklyn. Many of its physicians are regularly rated among the best in New York City. Some are known throughout the world.

SUNY Downstate Medical Center enters the new century with a renewed dedication to serving the people of Brooklyn through its three-fold mission of education, research, and patient care.

Synaerion is committed to deliver tangible and decisive therapeutic interventions to patients with incurable neurologic disorders. Our technology leverages the therapeutic potential of a dual-target technology based on the disease-modifying potential of a key signal transduction brain factor. We are developing a new class of small molecules for the treatment of neurodegenerative disorders, initially amyotrophic lateral sclerosis (ALS aka Lou Gehrig Disease) and traumatic brain injury (TBI), expanding to Alzheimer’s disease and multiple sclerosis (MS). Therapeutic options for ALS and TBI patients are inadequate with only Rilutek® approved for ALS and none for TBI. Regenerative therapy (stem cell or mesenchymal cell transplants) is a promising new approach though still concerning for its "uncontrolled" mid/long-term safety. Synaerion's technology has the (upstream) benefit of a cell therapy with manageable long-term safety, combined with the ALS/TBI pathogenic target (downstream) effects. Synaerion's is the first and only disease-modifying dual-target technology tested in symptomatic ALS/TBI animals. We are developing two lead compounds for ALS and TBI, leveraging a rich pipeline for development in other therapeutic areas and a discovery research platform for novel NCEs.

More Information Website: http://www.synaerion.com

Syndax is a clinical stage biopharmaceutical company developing entinostat as a combination therapy in multiple cancer indications with an initial focus on tumors that have shown sensitivity to immunotherapy, including lung cancer, melanoma and triple negative breast cancer. Entinostat is an oral, small molecule drug candidate that has direct effects on both cancer cells and immune regulatory cells, potentially enhancing the body’s immune response to tumors. 

We are developing the first GI platform based on uroguanylin – a naturally occurring human peptide that plays a key role in regulating normal digestive activity

TNT (Tactile Navigation Tools, LLC) creates and commercializes superior assistive technology for those with visual impairment. Currently, the tools and devices offered are antiquated and inadequate for the challenges of the visually disabled, preventing health optimization by many. 

We have tools that simplify training, increase mobility, and permit functional independence. The founder is a disability physician living with visual impairment and the team combines rehabilitation medicine, engineering, computer modeling and psychophysics.