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YOUR INNOVATIVE SOLUTION:

AXENIS business model is based on the following three ideas :

-Central focus on humanized mouse models and their applications;

-Feed the flow of in-licensed new models and innovations in order to generate the richest possible catalogue of humanized models and pre-clinical studies and accumulate latest models and

related knowledge

-Offer pre-clinical studies to the biopharma industry.

 

WHICH PROBLEM ARE YOU SOLVING?

-Human immuno-profiling for drug discovery and validation;

-Searching for and validating predictive biomarkers of disease progression or resolution (infection, autoimmunity, tumor control…);development/Validation of vaccine, biologicals, small molecules, adjuvants and mAb treatments;

 

TARGET PARTNERS:

Partners/Licensing of immunodeficient mice :

Ø  PDX models/Sell

Ø  US/Asia/India/Europa

Ø  Co-development of new combine models (Liver/Tumor/Muscle..)

 

KEY VALUE PROPOSITION:

It will specialize in bringing the newest validated models to its clients and exploiting these models through in-house experimental studies. The vision of the founders is to make AXENIS a world-wide leading service company in humanized models.

i2a Founded over 25 years ago, i2a develops microbiology instruments, software, reagents and consumables. i2a is now launching a Total Bacteriology Lab Automation solution. Industry sectors Medtech Therapeutics Area Immunology
Infectious Diseases - Vaccines
Ivd / Diagnostics
Your innovative solution

i2a is a company working on microbiology automation. The objective is to offer a global solution from the arrival of samples to the final results. i2a manufactures and sells pre-analytical device, automatic incubator automatic reader-incubator, software, reagents and consumables. The current total bacteriology automation proposed by i2a strengthens quality, optimizes sample flow, enhances flexibility and reduces costs.

Which problem are you solving ?

Each clinical microbiology laboratory is unique and its organization may vary, but they all have seen a 10 

Target market segments

Market segment 1: Hospital Clinical Lab of Microbiology Market segment 2: Reference Lab of Microbiology Market segment 3: Small and Medium Private Lab of Microbiology

Key value proposition

Advantage 1: Strenghten quality Advantage 2: Enhance flexibility Advantage 3: Optimize sample flow Advantage 4: Reduce costs

B Cell Design promotes a new approach of mucosal immunotherapies. The innovation is based on a technology platform to generate a large number of drug and vaccine candidates in infectious diseases and oncology.

The preferential tropism of class A isotype for mucosal compartments is the key in treatment of infectious diseases and mucosal cancers (gut, lung) strategies.  Its high resistance (under its secretory form) through the entire digestive tracts, allow an oral administration of anti-cancer immunotherapy. B CELL DESIGN develops a new concept of therapeutic IgA and secretory IgA for anti-colorectal cancer therapy and medical imaging of early-stage metastasis. To target AIDS, B Cell Design develops an alternative vaccine approach for a mucosal induction of a neutralizing response, at the gate of entrance of the virus.

Based on an innovative platform of humanized transgenic mice models, B CELL DESIGN offers a complete panel of specific monoclonal antibodies, hIgG1, hIgA1, hIgA2, SIgA1, hIgM and hIgE. The main issue in the diagnostic industry is to solve the problem of supply in specific human sera, as positive controls and calibrators for their diagnostic kits. Plus, for some diseases, patients developed a combined immune response, requiring testing various isotypes. B CELL DESIGN offers secure solutions to overcome supplying restraints. Working with monoclonal antibodies offers a perfect reproducibility of antibodies affinity, allows keeping quality track of all components of the kit, and ensures a complete safety for users because of a non-human cellular manufacturing system.

 

OBJECTIVES :

B CELL DESIGN is seeking for partners to pursue the development of our drug candidates and to  initiate new projects based on our technological platform.

CREAPHARM GROUP Providing customized international clinical supplies solutions to meet your needs & Improving your patients

CreaPharm group is a customer-focused team of 164 people applying their expertise and innovative solutions to offer a first-class service to their 250 active customers.

We are a mid-size subcontractor that is big enough to offer high range of services of the highest quality while at the same time being small enough to offer dedicated care and to adapt its processes according to the specificities of each client request.

Our 4 facilities are fully compliant with Good Manufacturing Practices and Good Distribution Practices and are inspected by the French medicines agency ANSM for human medicinal products and the ANSES for veterinary products.

Our team has years of experience in managing all types of projects with agility, flexibility and responsiveness.

Clinical Supplies:

·         GMP manufacturing,

·         Packaging and labelling,

·         International distribution,

·         Comparator and ancillary goods sourcing,

·         IMP importation and QP release services,

·         Biological sampling kit production

 

Pharmaceutical Contract Manufacturing:

·         Packaging design and development, Packaging of market drugs,

·         Special packing and repacking activities,

·         Late stage customization

 

Cosmetic Contract Manufacturing:

·         Formulation of cosmetic products,

·         A wide range of formulas available,

·         Packaging design and development, Manufacturing & packaging of cosmetic products

Care Labs Edition, management and marketing of prepaid voucher : healthcare voucher Industry sectors E health Therapeutics Area Dental and Oral Health
Dermatology
Nutrition and Weight Loss
Orthopedics/Orthopedic Surgery
Psychiatry/Psychology
Your innovative solution

CHEQUE SANTE

Which problem are you solving ?

The costs of healthcare become more and more disabling for the modern-day families. Because of these costs, they tend to avoid taking medical appointments. Our objective is to allow every individual to be the master of his own health capital.

Target market segments

Firms, Works Council, Mutual insurance companies, Insurances?

Key value proposition

Prepaid voucher, Online appointment setting, Intelligent health record, Directory of the healthcare professionals

CLEVEXEL Pharma invests its teams' know-how to catalyze innovative drug development projects and ensure their attractiveness on the market.

We are an integrated, one-stop-shop solution for the co-development of promising new therapeutic compounds. We partner with inventors to boost the development of their product from proof-of-concept in an animal model to proof-of-concept in human. The project is then outlicensed to a pharmaceutical company for Phase III and Market Access.

HYBRIGENICS Hybrigenics is a biopharmaceutical company involved in the discovery and the development of new anticancer drugs. Industry sectors Biotech Therapeutics Area Oncology
Your innovative solution

Hybrigenics is developing inecalcitol, a vitamin D receptor agonist, characterized by enhanced activities against cancer cell proliferation and much reduced toxicity on blood calcium levels as compared to calcitriol, the active form of vitamin D. Therefore, inecalcitol can be given at high daily oral doses which exert cytostatic effects on tumors. 

Which problem are you solving ?

Acute myeloid leukemia (AML) has the worse prognosis of all types of leukemias (<25% 5-year survival). Furthermore, elderly or frail AML patients cannot support standard induction chemotherapy and are eligible only to treatment with either decitabine or azacytidine, two hypo-methylating agents. The goal is to increase overall survival of these desperate patients by adding daily oral inecalcitol to hypo-methylating therapy.

Target market segments

Pharmaceutical products / anticancer agents / hematological malignancies / small chemical drugs /

Key value proposition

Orphan drug status already granted for AML in US and EU / Excellent tolerance in patients / convenient daily oral dosing favoring compliance / Strong proof of principle in animal AML models

Olmix is a marine biotechnology specialist providing algae-based therapeutic solutions in CNS, oncology and immunology.

AN UNIQUE INNOVATIVE SOLUTION

Olmix group has developed specific knowledge and technologies to extract and select algal molecules of interest for animal and plant health. Some of these molecules can also be beneficial for human health and one of them has been identified as a potential antidepressant for humans.                                             

We have found in algae a new antidepressant molecule which from what we know at the moment provide beneficial effects against depression without any undesirable side effect.

 

KEY VALUE PROPOSITION

• Efficient Natural solution
• No side effect
• Easy to produce

TARGET MARKET SEGMENTS

• Central Nervous system             
• Antidepressant
• Other applications and compounds in oncology and immunology

 

TARGET PARTNERS

• Co-development partners with interest in described therapeutic areas
• Investors (Corporate funds, VC...)

AMA, 1 in 10 companies certified "Glass Partner" by Google worldwide, provides mobile and hands-free tele-expertise solutions on smart glasses, mainly in the medical fields. Industry sectors E_health Therapeutics Area Cardiology / Vascular Diseases
CNS-Neurology
Dermatology
Gastroenterology / Hepatology
Orthopedics/Orthopedic Surgery
Pediatrics/Neonatology
Your innovative solution

Hands-free, mobile audio-video connection on smart glasses through a HIPAA exchange platform allowing the physician to communicate with the patient and nurse, permitting synchronous tele-consultations. Doctors can take pictures remotely, select areas within the photo to highlight, comment on and transfer to the nurse and patient file.

Which problem are you solving ?

-TELEMEDICINE: AMA's solution brings healthcare expertise to patients, eliminating geographical constraints and improving quality care and patient comfort. - FINANCIAL challenges: reduces transport, hospitalisation costs and time consumption. - EMERGENCY: fast intervention, doubt removal, orientation to best-fitting hospital - E-LEARNING and mentoring: Live and personalised advice and guidance during training/interventions

Target market segments

Emergency 1 / Ambulances 2 / Nursing homes 3 / E-training 4

Key value proposition

Mobility 1 / Hands-free 2 / Videoconferencing (audio - video exchanges) 3 / Efficient (cost and time saving) 4

Contacts:

• Jean-François DENIS, VP Sales
• Anne-Fleur ANDRLE, Business Development US

Nano-H AGuIX: the nanomedicine solution to improve MRI-guided radiation therapy Industry sectors Biotech Therapeutics Area Oncology
Your innovative solution

AGuIX is a Gadolinium nanoparticle, injectable by IV, that improve MRI-guided radiation therapy, allowing personalized medicine for an optimize radiation treatment. Eliminated by the kidneys without toxicity, AGuIX allow within a single injection tumor delineation and enhancement of treatment efficacy.

Which problem are you solving ?

Radiation therapy can generates toxicity in the organs surrounding the tumor and CT images are not specific in soft tissue areas. AGuIX enhance the tumor delineation under MRI by enhancing the contrast and boost the effect of the radiation in the tumor. AGuIX can enhance treatment efficacy and might be use to reduce the planned dose to spare the healthy organs.

Target market segments

1/ Radiation Oncology 2/ Contrast Agent 3/ Compagnon diagnosis

Key value proposition

1/ Radiosensitizer 2/ MRI agent 3/ Personalized medicine / Various injection mode